Cancer Research
Breakthrough oncology research, immunotherapy advances, early detection science, and cancer prevention evidence.
28 articles
Liquid Biopsy: How Blood-Based Cancer Detection Actually Works Today
Liquid biopsy tests detect tumor DNA fragments circulating in blood, offering a less invasive alternative to tissue biopsy. Here is what these tests can reliably do today, and where multi-cancer early detection remains unproven.
Aug 2, 2026
Why Colorectal Cancer Screening Guidelines Lowered the Starting Age to 45
Major guidelines now recommend colorectal cancer screening beginning at 45 rather than 50, driven by a documented rise in early-onset cases. Here is what the data actually shows and what changed in the guidance.
Aug 2, 2026
Companion Diagnostics: How Testing and Targeted Cancer Therapy Get Matched
Nearly every modern targeted cancer therapy is paired with a specific, FDA-approved diagnostic test. Here is how this co-development model actually works and why it matters for treatment access.
Jul 31, 2026
AI-Powered Pathology: Digital Slide Analysis and the Future of Cancer Diagnosis
Whole-slide imaging and AI analysis are transforming how biopsies get read, offering faster turnaround and more consistent grading. Here is where digital pathology stands and what is still holding back adoption.
Jul 1, 2026
Why Colorectal Screening Uptake Still Lags Among Newly Eligible 45-49 Year Olds
Rising early-onset colorectal cancer rates prompted a guideline change lowering the screening age to 45. Uptake, however, remains stubbornly below target.
Jun 22, 2026
CAR-T Cell Therapy: How Personalized Cancer Treatment Actually Works
CAR-T therapy re-engineers a patient's own immune cells to hunt cancer. Here is the actual biological process behind it, what conditions it treats today, and why manufacturing remains such a bottleneck.
Jun 17, 2026
Colorectal Cancer Screening in 2025: Colonoscopy vs. Cologuard vs. FIT — Updated Evidence
Updated clinical guide to CRC screening options — the NordICC colonoscopy trial controversy, Cologuard sensitivity/specificity, FIT evidence, and current USPSTF recommendations for shared decision-making.
Jun 12, 2026
At-Home HPV Screening: Self-Collected Tests Are Now FDA-Cleared and Clinically Validated
FDA clearance of self-collected vaginal swabs for HPV testing in 2024 has opened cervical cancer screening to millions of women who avoid clinical pelvic exams. In 2026, Teal Health's Teal Wand is in national rollout. We examine the accuracy data and what it means for cancer prevention.
May 28, 2026
CAR-T Cell Therapy for Lupus and Autoimmune Disease: Beyond Cancer, a New Frontier
CAR-T cells engineered to deplete autoreactive B cells are achieving unprecedented remissions in severe lupus, systemic sclerosis, and myositis — conditions where standard immunosuppression has failed for decades. The 2026 clinical landscape is rewriting the prognosis for patients with refractory autoimmune disease.
May 26, 2026
Histotripsy: The Ultrasound Technique That Liquefies Tumors Without Heat or Incisions
Histotripsy — the first FDA-cleared non-thermal focused ultrasound technology — uses acoustic cavitation to mechanically destroy liver tumors from outside the body. In 2026, the HistoSonics HOPE4LIVER trial data is driving rapid adoption and expansion to new indications.
May 24, 2026
CAR-T Therapy Expands Beyond Blood Cancers Into Solid Tumors
CAR-T cell therapy revolutionized leukemia and lymphoma treatment. New engineering approaches are finally showing promise against historically resistant solid tumors.
May 21, 2026
Young-Adult Colorectal Cancer: Why Cases Are Rising in People Under 50 and What to Do About It
Colorectal cancer incidence in adults under 50 has increased 51% since 1994, prompting the USPSTF to lower the screening age to 45 and spurring research into microbiome dysbiosis, ultra-processed food, and novel early detection strategies for younger patients.
May 18, 2026
Lung Cancer Screening with Low-Dose CT: Updated USPSTF Guidelines and Eligibility in 2025
Current evidence on lung cancer screening with LDCT — NLST, NELSON trial data, updated USPSTF 2021 eligibility criteria, and what primary care providers need to know for eligible patients.
May 5, 2026
mRNA Cancer Vaccines: Where Personalized Immunotherapy Stands in 2026
Personalized mRNA vaccines targeting a patient's specific tumor mutations are showing durable results in melanoma and pancreatic cancer trials. We review the latest data.
Apr 20, 2026
Cancer Immunotherapy in 2025: Checkpoint Inhibitors, CAR-T, and What Response Rates Really Mean
Evidence-based guide to cancer immunotherapy — how checkpoint inhibitors work, response rate definitions and their limitations, FDA-approved indications by tumor type, and managing immune-related adverse events.
Apr 17, 2026
Exercise Oncology in 2025: The Evidence for Physical Activity During and After Cancer Treatment
Evidence-based review of exercise as cancer medicine — the CHALLENGE and DARE trials, cancer-related fatigue evidence, survivorship exercise programs, and ACSM exercise oncology guidelines.
Mar 25, 2026
Precision Oncology in 2025: Biomarker-Driven Therapy Selection and Molecular Testing Advances
Clinical guide to precision oncology — comprehensive genomic profiling, tumor mutational burden, microsatellite instability, PD-L1 testing, and how molecular biomarkers guide targeted therapy selection.
Mar 19, 2026
Liquid Biopsy Cancer Screening Moves Into Routine Checkups
Multi-cancer early detection blood tests are moving from research settings into annual physicals, promising to catch dozens of cancer types before symptoms appear.
Mar 19, 2026
CAR-T Therapy Expands: The Push to Treat Solid Tumors After Blood Cancer Success
CAR-T cell therapy revolutionized blood cancer treatment. The scientific challenge and progress in extending this living medicine to solid tumors.
Feb 13, 2026
Personalized Cancer Vaccines: How mRNA Technology Targets Individual Tumors
mRNA cancer vaccines custom-designed to each patient tumor are showing promise in trials. How they work and why they may prevent recurrence.
Feb 11, 2026
Multi-Cancer Early Detection Tests: The Promise and Caveats of Screening Blood Tests
Blood tests that screen for many cancers at once could transform early detection. The genuine promise and the important unresolved questions about overdiagnosis.
Feb 9, 2026
Antibody-Drug Conjugates: The Smart Bombs Reshaping Cancer Chemotherapy
Antibody-drug conjugates deliver potent chemotherapy directly to cancer cells while sparing healthy tissue. How this targeted approach is expanding treatment options.
Feb 7, 2026
Cancer Survivorship: Managing the Long-Term Health After Treatment Ends
More people survive cancer than ever, but treatment leaves lasting effects. The growing field of survivorship care addressing life after cancer.
Feb 5, 2026
Non-Invasive Colorectal Cancer Screening: Weighing the Alternatives to Colonoscopy
Updated clinical guide to colorectal cancer screening — comparative effectiveness of colonoscopy, FIT, Cologuard (mt-sDNA), and CT colonography, with USPSTF 2023 guidelines and risk stratification.
Dec 28, 2025
CAR-T Cell Therapy: The Cancer Treatment That Reprograms Your Own Immune System
Chimeric antigen receptor T-cell therapy is producing durable remissions in patients with previously incurable blood cancers — and is now moving aggressively into solid tumors.
May 28, 2025
Liquid Biopsy: How a Simple Blood Test Is Revolutionizing Early Cancer Detection
Circulating tumor DNA in the bloodstream can now detect multiple cancer types years before symptoms appear. Liquid biopsy is on the verge of transforming oncology screening.
May 15, 2025
Proton Beam Therapy: The Precision Radiation Sparing Healthy Tissue
Unlike conventional X-ray radiation, protons deposit their energy precisely at the tumor and stop — dramatically reducing radiation dose to surrounding healthy tissue and enabling treatment of previously inoperable cancers.
Apr 7, 2025
CRISPR and Cancer: What the Latest Clinical Trials Are Showing in 2025
From editing CAR-T cells to directly targeting tumor driver mutations, CRISPR gene editing is entering cancer clinical trials at an accelerating pace. The results so far are cautiously extraordinary.
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